Dieters are a humorous breed, and by many standards may very well be categorised as insane. The exception to the rule is the DOT1 household, members of which methylate K79 within the globular area of histone H3 and which are structurally not associated to SET-area proteins four - 6 Current work means that SET-domain-containing proteins methylate a couple of proteins in addition to histones (see later)
